The Cell Process Team is seeking a talented, diligent, and collaborative research associate to execute and design cell expansion process activities for the advancement of our best-in-class CAR-NK Cell Therapies for Oncology and other diseases. Cell Process works to ingeniously solve the challenges associated with the allogeneic manufacture of CAR-NK cell therapies including cell isolation/enrichment; cell engineering and gene editing; and cell expansion. They will be responsible for the operation of a clinical-scale bioreactor process design for the expansion of clinical CAR-NK candidates, execution of cell-based assays for in-process characterization, and technical process transfer to internal and external manufacturing sites in support of Phase 1 clinical activities.
The ideal candidate is a self-motivated and technically competent process development scientist or engineer with an interest in bioreactor design and control, who is excited to join a small, fast-paced team with a “can-do” attitude to drive forward our new cell therapy platform. This is a unique opportunity to realize the promise of allogeneic cell therapy manufacturing paradigms and bring the TAILWIND platform to life at a clinical scale.
- Execute experiments under supervision and independently in cross-functional teams, to drive bioprocess development for CAR-NK cell therapies
- Perform analyses of cell biology and functions using a variety of cell-based assays and analytical methods
- Analyze and interpret data to support company-wide activities including cell engineering research and cell production
- Meticulously maintain records, generate reports, records, and documents for IP and regulatory filings
- Present results to scientific team and management as well as external meetings
- Actively contribute to building a positive, team-oriented, startup biotech culture; participate in the active exchange and challenge of scientific ideas
Education, Experience, and Qualifications
- Bachelors or master’s degree in chemical engineering, immunology, biology, synthetic biology, chemical biology, biochemistry, pharmaceutical sciences, bioengineering, or equivalent/related disciplines
- 0-2 years’ experience in industry or academia
- Demonstrated understanding and technical skills in one or more of the following: primary human immune cell culture; bioreactor design and control; scale-up parameters; scale-down models; cryopreservation; buffer-exchange processes; fill-finish operations; and other experience in cell process development
- Excellent communication and presentation skills, capable of conveying complex biological data to non-experts
- Attention to detail and demonstrated ability in multi-tasking and thriving in teams with diverse technical expertise
- Highly preferred but non-essential qualifications:
- Experiences in cell therapy
- Experience in flow cytometry, multiplex analysis, and in vitro assessment of immune cells
- Experience in NK cells, electroporation, and transposon systems
- Experience in publishing and/or presenting in public scientific forums (papers, posters, conference talks)
Catamaran Bio is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.